Содержание
Количество страниц,
Год издания,
Переплет,
ISBN,
язык,
От автора
Количество страниц
368
Год издания
2009
Переплет
Твердый переплет
ISBN
0444532293
язык
Английский
От автора
Morphological and functional studies revealed a complex system of primary sensory neurons which parallels the autonomic nervous system not only in its extent, but probably also in its significance. Neuropeptides released from activated nociceptive afferent nerves play a pivotal role in inflammatory reactions and pain, significantly modulate cardiac, vascular, respiratory, gastrointestinal and immune functions and influence the protective, restorative and trophic functions of somatic and visceral tissues. Several chapters of the book deal with the therapeutic potential of a new class of putative pain relieving agents acting through TRPV1, the capsaicin/vanilloid receptor, a specific ion channel which transmits pain. * Neurogenic inflammation in historical perspective* Cardiac protection by nociceptive afferents* Molecular mechanisms of nociception* Sensory mechanisms in migraine pathophysiology* Vagal signalling of visceral inflammation* Neurogenic mechanisms in arthritis* Therapeutic implications of vanilloid-type compounds
